EKF Molecular Diagnostics and GILUPI announce CTC DNA enrichment success
EKF Molecular Diagnostics, and GILUPI, an innovator in medical devices for in vivo isolation of rare cells directly from a patient’s blood stream announces results from collaborative work using GILUPI CellCollectorTM and EKF Molecular’s PointManTM DNA Enrichment technology.
The first results of a collaboration between EKF Molecular Diagnostics and GILUPI has successfully demonstrated the detection of gene mutations from as few as three or less cells isolated in a model in vitro system and from the blood of lung cancer patients.
PointMan DNA Enrichment was used to detect and analyse cells with known mutation status that had been collected on GILUPI CellCollectors under laboratory conditions. The known mutations were those typically seen in lung (EGFR) and colorectal (KRAS) cancer.
Positive results using PointMan assays for KRAS (codon 12/13) and EGFR (T790M and L858R) from cell lines with known mutations and patients wer