EKF highlights ultra-sensitive cancer mutation detection kits at AACR 2014

EKF Diagnostics, the global in vitro diagnostics business, will be present on Booth #438 at AACR 2014 (American Association of Cancer Research), 5-9th April, San Diego. EKF Molecular will exhibit its PointMan™ DNA-enrichment technology, which enables ultra-sensitive and highly-specific cancer mutation detection unmatched by existing technologies.

PointMan™ is an extremely sensitive and selective tool based on real-time PCR technology that can enrich mutations from limited sample material. This is vital for a companion diagnostic, particularly in oncology, where the availability of tumour biopsy tissue is restricted.

In collaboration with Swansea University, EKF Molecular is currently investigating the ability of PointMan™ kits to enrich mutant DNA from a blood-based sample. Initial results have demonstrated the detection of gene mutations in blood samples archived in the Wales Cancer Bank.

EKF Molecular has a growing range of products and technologies developed to meet an increasing demand for superior sensitivity and specificity in molecular diagnostics.

PointMan™ DNA enrichment kits are available to detect various mutations for cancer biomarkers, including BRAF, KRAS, EGFR, NRAS, and JAK2. These genes are associated with skin melanoma, colorectal and lung cancers, and myeloma.

For more information on EKF Diagnostics and its molecular division, please visit www.ekfdiagnostics.com or www.ekfmolecular.com.